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Nayzilam nasal spray is a prescription medicine used short term to treat seizure clusters (also called acute repetitive seizures ) in adults and children at least 12 years old. This nasal spray can be given during or immediately after the fi rst seizure if a cluster occurs, even if the person is unconscious—no inhaling is necessary. Nayzilam nasal spray midazolam nasal spray is commercially available under the brand name of nayzilam®

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For many years, doctors have prescribed compounding formulations of midazolam to use with a generic nasal atomizer You don’t have to wait to treat a seizure cluster with nayzilam This branded form is more concentrated and easier to use.

Nayzilam is easy to administer and can quickly treat seizures that occur outside of the hospital

Highlights of prescribing information s do not include all the informa ion needed to u for nayzilam® Nayzilam® (midazolam) nasal spray, civ initial u.s And dependenc see full prescribing information for complete boxed warning. Nayzilam produces a calming effect on the brain and nerves, which helps to treat seizures

How is nayzilam supplied (dosage forms) Nayzilam is available as a 5 mg nasal spray For nasal dosage form (spray) Adults and children 12 years of age and older—5 milligrams (mg) or 1 spray into one nostril

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A second spray may be taken 10 minutes after the first dose if needed

Do not use a second dose if you have trouble breathing or excessive sleepiness during a seizure cluster episode. See full prescribing information for nayzilam® Risks from concomitant use with opioids see full prescribing information for complete boxed warning Concomitant use of benzodiazepines and opioids may result in profound sedation, respiratory depression, coma, and death.

Each nasal spray device has 5 milligrams (mg) in 0.1 milliliters (ml) of solution Usually prescribed as 1 spray into one nostril If seizures continue after 10 minutes, a second spray may be given into the other nostril, if prescribed by the healthcare provider Do not use more than 2 doses to treat one seizure cluster, unless specifically instructed by your healthcare provider

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